Clinicopathologic Features of Non–Small-Cell Lung Cancer Harboring an <i>NTRK</i> Gene Fusion

Abstract

<i>NTRK</i> fusions occur in NSCLCs across genders, ages, smoking histories, and histologies. Given the potent clinical activity of TRK inhibitors, we advocate that all NSCLCs be screened for <i>NTRK</i> fusions using a multiplexed NGS-based fusion assay.