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Stabilization of the hypoxia-inducible transcription Factor-1 alpha (HIF-1α) in thiamine deficiency is mediated by pyruvate accumulation

Pyruvate AccumulationTranscriptional RegulationBiochemistryRedox RegulatorNatural SciencesGeneticsPhysiologyHypoxia (Medicine)MetabolismGene ExpressionMedicineRedox BiologyThiamine DeficiencyOxidative Stress