Solid Lipid Nanoparticles Enhance the Delivery of the HIV Protease Inhibitor, Atazanavir, by a Human Brain Endothelial Cell Line

Niladri Chattopadhyay, Jason Zastre, Ho-Lun Wong, +2

Pharmaceutical Research

NanoparticlesNanomedicineLipid PreparationEngineeringTherapeutic Nanomaterials +8

Linking vitamin B1 with cancer cell metabolism

Jason Zastre, Rebecca Sweet, Bradley S. Hanberry, +1

Cancer & Metabolism

NutritionChemoprevention StrategyMetabolic RemodelingCancer BiologyTumor Biology +20

Up‐regulation of P‐glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line

Jason Zastre, Gary N. Y. Chan, Patrick T. Ronaldson, +6

Journal of Neuroscience Research

Enhanced cellular accumulation of a P-glycoprotein substrate, rhodamine-123, by caco-2 cells using low molecular weight methoxypolyethylene glycol-block-polycaprolactone diblock copolymers

Jason Zastre, John K. Jackson, Mandeep Bajwa, +3

European Journal of Pharmaceutics and Biopharmaceutics

Caco-2 CellsEngineeringEnhanced Cellular AccumulationBiochemistryP-glycoprotein Substrate +8

Deferiprone protects against doxorubicin-induced myocyte cytotoxicity

Norman Barnabé, Jason Zastre, S. Venkataram, +1

Free Radical Biology and Medicine

InflammationDrug ResistanceMedicineTherapeutic EfficacyPharmacotherapy +3

Synthesis and micellar characterization of short block length methoxy poly(ethylene glycol)-block-poly(caprolactone) diblock copolymers

Kevin Letchford, Jason Zastre, Richard Liggins, +1

Colloids and Surfaces B Biointerfaces

Materials ScienceEthylene GlycolPolymer MaterialEngineeringBlock Co-polymers +9

Role of Drug Efflux and Uptake Transporters in Atazanavir Intestinal Permeability and Drug-Drug Interactions

Olena Kis, Jason Zastre, Md. Tozammel Hoque, +2

Pharmaceutical Research

Gastrointestinal PharmacologyMedicinePhysiologyPharmacologyAtazanavir Intestinal Permeability +4

High-dose vitamin B1 reduces proliferation in cancer cell lines analogous to dichloroacetate

Bradley S. Hanberry, Ryan R. Berger, Jason Zastre

Cancer Chemotherapy and Pharmacology

High-dose Vitamin B1OncologyCancer Cell LinesChemoprevention StrategyOncogenic Agent +8

Hypoxia induced upregulation and function of the thiamine transporter, SLC19A3 in a breast cancer cell line

Rebecca Sweet, Amber M. Paul, Jason Zastre

Cancer Biology & Therapy

P-Glycoprotein Efflux Inhibition by Amphiphilic Diblock Copolymers: Relationship between Copolymer Concentration and Substrate Hydrophobicity

Jason Zastre, John K. Jackson, Wesley Wong, +1

Molecular Pharmaceutics

Pharmaceutical ScienceEngineeringNarrow Concentration RangeSubstrate HydrophobicityCopolymer Concentration +14