Interleukin-1 beta promotes neuronal differentiation through the Wnt5a/RhoA/JNK pathway in cortical neural precursor cells

Interleukin 1 signaling occurs exclusively via the type I receptor.

John E. Sims, Margit Gayle, Jennifer L. Slack et al. · Proceedings of the National Academy of Sciences · 1993 · 610 citations · Full text

Immunology, Immune Regulation, Immunologic Mechanism +16

Proinflammatory cytokine synthesis in the injured mouse spinal cord: Multiphasic expression pattern and identification of the cell types involved

Isabelle Pineau, Steve Lacroix · The Journal of Comparative Neurology · 2006 · 595 citations

Regulation of Dendritic Growth and Remodeling by Rho, Rac, and Cdc42

Richard Threadgill, Kathryn Bobb, Anirvan Ghosh · Neuron · 1997 · 492 citations · Full text

Neuroprotective Effects of Human Recombinant Interleukin-1 Receptor Antagonist in Focal Cerebral Ischaemia in the Rat

Sarah A. Loddick, Nancy J. Rothwell · Journal of Cerebral Blood Flow & Metabolism · 1996 · 461 citations · Full text

Immunology, Cerebrovascular Disease, Cerebral Vascular Regulation +27

Inflammatory cytokines IL-1 alpha, IL-1 beta, IL-6, and TNF-alpha impart neuroprotection to an excitotoxin through distinct pathways.

Noel G. Carlson, Whitney A. Wieggel, Jian Chen et al. · PubMed · 1999 · 339 citations

Immunology, Cell Death, Oxidative Stress +21