Exercise Training Protects Against Aging-Induced Cognitive Dysfunction via Activation of the Hippocampal PGC-1α/FNDC5/BDNF Pathway

Analyzing real-time PCR data by the comparative CT method

Thomas D. Schmittgen, Kenneth J. Livak · Nature Protocols · 2008 · 26K citations

Computed Tomography, Image Analysis, Engineering +8

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

Pontus Boström, Jun Wu, Mark P. Jedrychowski et al. · Nature · 2012 · 4.6K citations · Full text

Exercise Enhances Learning and Hippocampal Neurogenesis in Aged Mice

Henriette van Praag, Tiffany E. Shubert, Chunmei Zhao et al. · Journal of Neuroscience · 2005 · 2.1K citations · Full text

Physical Activity, Aging, Voluntary Exercise +18

Cell Survival Promoted by the Ras-MAPK Signaling Pathway by Transcription-Dependent and -Independent Mechanisms

Azad Bonni, Anne Brunet, Anne E. West et al. · Science · 1999 · 1.9K citations

Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway

Christiane D. Wrann, James P. White, John Salogiannnis et al. · Cell Metabolism · 2013 · 1.3K citations · Full text

Molecular Neuroscience, Exercise, Exercise Physiology +6