Risk of meticillin resistant <i>Staphylococcus aureus</i> and <i>Clostridium difficile</i> in patients with a documented penicillin allergy: population based matched cohort study

Abstract

Documented penicillin allergy was associated with an increased risk of MRSA and <i>C difficile</i> that was mediated by the increased use of β lactam alternative antibiotics. Systematically addressing penicillin allergies may be an important public health strategy to reduce the incidence of MRSA and <i>C difficile</i> among patients with a penicillin allergy label.