Neuroprotection by ethanolic extract of Syzygium aromaticum in Alzheimer's disease like pathology via maintaining oxidative balance through SIRT1 pathway

Oxidative Damage Is the Earliest Event in Alzheimer Disease

Akihiko Nunomura, George Perry, Gjumrakch Aliev et al. · Journal of Neuropathology & Experimental Neurology · 2001 · 1.9K citations · Full text

Life Sciences, Neurology, Neuroscience +17

Characterization of Five Human cDNAs with Homology to the Yeast SIR2 Gene: Sir2-like Proteins (Sirtuins) Metabolize NAD and May Have Protein ADP-Ribosyltransferase Activity

Roy A. Frye · Biochemical and Biophysical Research Communications · 1999 · 805 citations

Life Sciences, Biochemistry, Molecular Biology +7

Retinoic acid-induced differentiation of cultured human neuroblastoma cells: a comparison with phorbolester-induced differentiation

Sven Påhlman, Aino-Inkeri Ruusala, L. Abrahamsson et al. · Cell Differentiation · 1984 · 579 citations

Life Sciences, Cell Biology, Oncology +9

Changes of some oxidative stress markers in the serum of patients with mild cognitive impairment and Alzheimer's disease

Manuela Pădurariu, Alin Ciobîcă, Lucian Hriţcu et al. · Neuroscience Letters · 2009 · 379 citations

Medicine, Neurology, Neuroscience +14

Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease

Rosa Resende, Paula I. Moreira, Teresa Proença et al. · Free Radical Biology and Medicine · 2008 · 344 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16