Concepedia

Design, synthesis and anticancer evaluation of acridine hydroxamic acid derivatives as dual Topo and HDAC inhibitors

Jiwei Chen, Dan Li, Wenlu Li, Jingxian Yin, Yueying Zhang, Zigao Yuan, Chunmei Gao, Feng Liu, Yuyang Jiang

Bioorganic & Medicinal Chemistry · 2018 · 51 citations · 33 references

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References

33

Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA.

Myoung Sook Kim, Mellissa Blake, Jin Hyen Baek et al. · PubMed · 2003 · 464 citations

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Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

Jay H. Kalin, Muzhou Wu, Andrea V. Gómez et al. · Nature Communications · 2018 · 233 citations · Full text

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Sequence‐specific potentiation of topoisomerase II inhibitors by the histone deacetylase inhibitor suberoylanilide hydroxamic acid

Douglas C. Marchion, Elona Biçaku, Adil Daud et al. · Journal of Cellular Biochemistry · 2004 · 186 citations

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Dual Targeting of Histone Deacetylase and Topoisomerase II with Novel Bifunctional Inhibitors

William Guerrant, Vishal Patil, Joshua C. Canzoneri et al. · Journal of Medicinal Chemistry · 2012 · 147 citations · Full text

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Valproic acid, a histone deacetylase inhibitor, enhances sensitivity to doxorubicin in anaplastic thyroid cancer cells

Maria Graziella Catalano, Nicoletta Fortunati, Mariateresa Pugliese et al. · Journal of Endocrinology · 2006 · 122 citations · Full text

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