Preventive effects of astragaloside IV and its active sapogenin cycloastragenol on cardiac fibrosis of mice by inhibiting the NLRP3 inflammasome

Inflammasome Activation of Cardiac Fibroblasts Is Essential for Myocardial Ischemia/Reperfusion Injury

Masanori Kawaguchi, Masafumi Takahashi, Takeki Hata et al. · Circulation · 2011 · 862 citations

Veterinary Medicine, Cardiology, Pathobiology +17

Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease

Fan Dong, Abhijit Takawale, Ji‐Won Lee et al. · Fibrogenesis & Tissue Repair · 2012 · 809 citations · Full text

Veterinary Medicine, Cardiology, Cell Biology +17

The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia–reperfusion injury

Øystein Sandanger, Trine Ranheim, Leif Erik Vinge et al. · Cardiovascular Research · 2013 · 512 citations

Life Sciences, Cardiology, Immunology +17

Deletion of Mineralocorticoid Receptors From Macrophages Protects Against Deoxycorticosterone/Salt-Induced Cardiac Fibrosis and Increased Blood Pressure

Amanda J. Rickard, James J. Morgan, Greg H. Tesch et al. · Hypertension · 2009 · 296 citations · Full text

Life Sciences, Endocrinology, Physiology +11

Modulation of fibroblast functions by interleukin 1: increased steady-state accumulation of type I procollagen messenger RNAs and stimulation of other functions but not chemotaxis by human recombinant interleukin 1 alpha and beta

AE Postlethwaite, Rajendra Raghow, G P Stricklin et al. · The Journal of Cell Biology · 1988 · 255 citations · Full text

Life Sciences, Cell Biology, Immunology +17