Monolayer culture of intestinal epithelium sustains Lgr5+ intestinal stem cells

Identification of stem cells in small intestine and colon by marker gene Lgr5

Nick Barker, Johan H. van Es, Jeroen Kuipers et al. · Nature · 2007 · 5.6K citations

Cell Lineage, Cell Specialization, Marker Gene Lgr5 +10

Designer matrices for intestinal stem cell and organoid culture

Nikolce Gjorevski, Norman Sachs, Andrea Manfrin et al. · Nature · 2016 · 1.4K citations · Full text

Medicine, Adult Stem Cell, Cell Culture +6

Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny

Xiaolei Yin, Henner F. Farin, Johan H. van Es et al. · Nature Methods · 2013 · 567 citations · Full text

Regenerative Medicine, Embryonic Stem Cell, Developmental Biology +8

Cloning and variation of ground state intestinal stem cells

Xia Wang, Yusuke Yamamoto, Lane Wilson et al. · Nature · 2015 · 198 citations · Full text

Developmental Biology, Medicine, Adult Stem Cell +4

Enteroid Monolayers Reveal an Autonomous WNT and BMP Circuit Controlling Intestinal Epithelial Growth and Organization

Curtis A. Thorne, Ina W. Chen, Laura E. Sanman et al. · Developmental Cell · 2018 · 171 citations · Full text

Developmental Biology, Signal Transduction, Enteroid Monolayers Reveal +11