Ilixadencel – an Allogeneic Cell-Based Anticancer Immune Primer for Intratumoral Administration

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells

Sanjeev Mariathasan, Shannon J. Turley, Dorothee Nickles et al. · Nature · 2018 · 5.2K citations · Full text

Tumor Biology, Cancer Immunosurveillance, Tumour Response +12

Cisplatin plus Gemcitabine versus Gemcitabine for Biliary Tract Cancer

Juan W. Valle, Harpreet Wasan, Daniel H. Palmer et al. · New England Journal of Medicine · 2010 · 4.3K citations · Full text

Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trial

Jordi Bruix, Shukui Qin, Philippe Merle et al. · The Lancet · 2016 · 3.6K citations · Full text

Hepatology, Medicine, Sorafenib Treatment +8

An immunogenic personal neoantigen vaccine for patients with melanoma

Patrick A. Ott, Zhuting Hu, Derin B. Keskin et al. · Nature · 2017 · 2.8K citations · Full text

Vaccination, Tumor Immunology, Melanoma +5

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

Uğur Şahin, Evelyna Derhovanessian, Matthias Miller et al. · Nature · 2017 · 2.4K citations

Vaccination, Allergy, Medicine +11