Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation

T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma

Prescott G. Woodruff, Barmak Modrek, David F. Choy et al. · American Journal of Respiratory and Critical Care Medicine · 2009 · 1.8K citations · Full text

Life Sciences, Immunology, Internal Medicine +16

IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation

Suzanne M. Hurst, Thomas S. Wilkinson, Rachel M. McLoughlin et al. · Immunity · 2001 · 813 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Relationship between bacterial colonisation and the frequency, character, and severity of COPD exacerbations

Irem Patel · Thorax · 2002 · 697 citations · Full text

Medicine, Clinical Sciences, Internal Medicine +17

Defective epithelial barrier function in asthma

Xiao Chang, Sarah M. Puddicombe, Sarah A. Field et al. · Journal of Allergy and Clinical Immunology · 2011 · 633 citations

Life Sciences, Molecular Genetics, Physiology +12

Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort

Dominick Shaw, Ana R. Sousa, Stephen J. Fowler et al. · European Respiratory Journal · 2015 · 561 citations · Full text

Life Sciences, Immunology, Internal Medicine +16