Infection and Immunity · 2018 · 24 citations · 32 references
Life SciencesInfectious DiseasesMicrobiologyAutophagyHost-pathogen InteractionsMicrobial PathogenesisAutophagy In ImmunityBacterial Infection ProcessesBacterial PathogenesisBacterial Secretion SystemsMucosal PathogenesisPathogenesis Of Infectious DiseaseActin-based Cell MotilityActin-based MotilityAutophagy In Bacterial InfectionCell-to-cell MovementCell-to-cell SpreadInfection-induced AutophagyLc3 RecruitmentVirulence Secretion Mechanisms
Shigella flexneri disseminates within the colonic mucosa by displaying actin-based motility in the cytosol of epithelial cells. Motile bacteria form membrane protrusions that project into adjacent cells and resolve into double-membrane vacuoles (DMVs) from which the bacteria escape, thereby achieving cell-to-cell spread.
32
Escape of Intracellular <i>Shigella</i> from Autophagy
Michinaga Ogawa, Tamotsu Yoshimori, Toshihiko Suzuki et al. · Science · 2004 · 814 citations