A novel dicationic ionic liquid as a highly effectual and dual-functional catalyst for the synthesis of 3-methyl-4-arylmethylene-isoxazole-5(4H)-ones

4-[5-Methyl-3-phenylisoxazol-4-yl]- benzenesulfonamide, Valdecoxib:  A Potent and Selective Inhibitor of COX-2

John J. Talley, David Brown, Jeffery S. Carter et al. · Journal of Medicinal Chemistry · 2000 · 642 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Science +14

Synthesis and antioxidant activity of oxazolyl/thiazolylsulfonylmethyl pyrazoles and isoxazoles

Adivireddy Padmaja, Chittoor Rajasekhar, Akkarapalli Muralikrishna et al. · European Journal of Medicinal Chemistry · 2011 · 157 citations

Pharmacology, Heterocyclic, Antioxidant Activity +1

Synthesis and antibacterial activity of new carbapenems containing isoxazole moiety

Yong Koo Kang, Kye Jung Shin, Kyung Ho Yoo et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 148 citations

Medicinal Chemistry, Natural Sciences, Antibacterial Activity +8

Synthesis and antitumor activity of 2,5-bis(3′-indolyl)-furans and 3,5-bis(3′-indolyl)-isoxazoles, nortopsentin analogues

Patrizia Diana, Anna Carbone, Paola Barraja et al. · Bioorganic & Medicinal Chemistry · 2010 · 145 citations

Medicinal Chemistry, Natural Sciences, Medicine +7

Design, characterization and application of new ionic liquid 1-sulfopyridinium chloride as an efficient catalyst for tandem Knoevenagel–Michael reaction of 3-methyl-1-phenyl-1H-pyrazol-5(4H)-one with aldehydes

Ahmad Reza Moosavi‐Zare, Mohammad Ali Zolfigol, Mahmoud Zarei et al. · Applied Catalysis A General · 2013 · 113 citations

Chemical Engineering, Engineering, Organic Chemistry +6