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Fisetin Enhances the Cytotoxicity of Gemcitabine by Down-regulating ERK-MYC in MiaPaca-2 Human Pancreatic Cancer Cells

DOIFull Paper Access

23

Citations

23

References

2018

Year

Nayoung Kim, MIN-JUNG KANG, Sang Hyub Lee, Jun Hyuk Son, Ji Eun Lee, Woo Hyun Paik, Ji Kon Ryu, Yong-Tae Kim
Anticancer Research

Abstract

Fisetin sensitized human pancreatic cancer cells to gemcitabine-induced cytotoxicity through inhibition of ERK-MYC signaling. These results suggest that the combination of fisetin and gemcitabine could be developed as a novel potent therapeutic.

References

YearCitations

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