Concepedia

Suppression of T cells by mesenchymal and cardiac progenitor cells is partly mediated via extracellular vesicles

F. van den Akker, Krijn R. Vrijsen, Janine C. Deddens, Jan W. Buikema, Michal Mokrý, Linda W. van Laake, Pieter A. Doevendans, Joost P. G. Sluijter

Heliyon · 2018 · 45 citations · 51 references

DOIFull text

Open access

Concepts

Abstract

immunosuppression. This effect is mediated by paracrine factors, such as extracellular vesicles. Besides proliferation, many additional pathways are influenced by both BM-MSC and CMPC.

References

51

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love, Wolfgang Huber, Simon Anders · Genome biology · 2014 · 100.5K citations · Full text

, , +15

Human mesenchymal stem cells modulate allogeneic immune cell responses

Sudeepta Aggarwal, Mark F. Pittenger · Blood · 2004 · 4.5K citations · Full text

, , +13

Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli

Massimo Di Nicola, Carmelo Carlo‐Stella, Michele Magni et al. · Blood · 2002 · 3.2K citations · Full text

, , +10

Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide

Guangwen Ren, Liying Zhang, Xin Zhao et al. · Cell stem cell · 2008 · 2.1K citations · Full text

, , +14

Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase–mediated tryptophan degradation

Roland Meisel, Andree Zibert, M. D. Laryea et al. · Blood · 2004 · 1.6K citations · Full text

, , +13