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Sulfonamide Synthesis via Calcium Triflimide Activation of Sulfonyl Fluorides

DOIFull Paper Access

118

Citations

26

References

2018

Year

Paramita Mukherjee, Cristian P. Woroch, Leah Cleary, Mark Rusznak, Ryan Franzese, Matthew R. Reese, Joseph W. Tucker, John M. Humphrey, Sarah Etuk, Sabrina C. Kwan,
Organic Letters

Abstract

A method using calcium triflimide [Ca(NTf<sub>2</sub>)<sub>2</sub>] as a Lewis acid to activate sulfonyl fluorides toward nucleophilic addition with amines is described. The reaction converts a wide array of sterically and electronically diverse sulfonyl fluorides and amines into the corresponding sulfonamides in good yield.

References

YearCitations

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