Journal of Ophthalmology · 2018 · 24 citations · 17 references
MedicineOphthalmologySurgeryOcular AnatomyOphthalmic SurgeryRefractive SurgeryCataract ManagementCataract SurgeryRetinal AnatomyRetinal ExaminationRetinal Pigment EpitheliumRetinal SurgeryIntraoperative Optical Coherence TomographyOptical Coherence Tomography FindingsPostoperative Visual Outcome AssessmentRetinal Layer OrganizationRetinal Layer ThicknessRetinal Thickness AnalysisRetinal Thickness Mapping
Purpose . Our aim was to assess changes in the total retinal thickness (TRT), total retinal volume (TRV), and retinal layer thickness after uncomplicated cataract surgery. Methods . A total of 32 eyes of 32 patients who had undergone uncomplicated phacoemulsification surgery and intraocular lens implantation in one eye were enrolled. Effective phacoemulsification time (EPT) and total energy (TE) were recorded. Thickness and TRV were measured using optical coherence tomography. Data were collected preoperatively and at postoperative day 1, 7, 30, 90, and 180. Results . The study results showed a decrease in TRT, TRV, and most retinal layer thicknesses at the first postoperative day visit and then increasing at week 1, and months 1 and 3, and then relatively decreasing at month 6 although not returning to preoperative levels. The least affected layers were the retinal pigment epithelium and outer plexiform layer. There was a positive correlation between EPT and TE and ganglion cell layer in a 1 mm circle and inner nuclear layer in a 1–3 mm circle (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mrow><mml:mi>p</mml:mi><mml:mo><</mml:mo><mml:mn>0.05</mml:mn></mml:mrow></mml:math>). Conclusion . The results suggest that long-term follow-up of more than 6 months is necessary after cataract surgery to see whether total retinal and segmental values return to preoperative levels. This study was registered with Australian New Zealand Clinical Trials Registry (ANZCTR): ACTRN12618000763246 .
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Retinal inner nuclear layer volume reflects response to immunotherapy in multiple sclerosis
Benjamin Knier, Paul J. Schmidt, Lilian Aly et al. · Brain · 2016 · 119 citations
Medicine, Neurology, Ophthalmology +17