Inhibition of endocannabinoid degradation rectifies motivational and dopaminergic deficits in the Q175 mouse model of Huntington’s disease

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

Marcy E. MacDonald · Cell · 1993 · 8.4K citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

Manish A. Shah, Nicole A. Datson, Lakshmi Srinidhi et al. · Cell · 1993 · 3.1K citations

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Progressive Ratio as a Measure of Reward Strength

William Hodos · Science · 1961 · 1.1K citations

Public Health, Behavioral Sciences, Psychology +17

Differential loss of striatal projection neurons in Huntington disease.

Anton Reiner, Roger L. Albin, Karen E. Anderson et al. · Proceedings of the National Academy of Sciences · 1988 · 1K citations · Full text

Medicine, Neurobiology, Neuroscience +17

Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

Jonathan Z. Long, Weiwei Li, Lamont Booker et al. · Nature Chemical Biology · 2008 · 938 citations · Full text

Medicine, Neuroscience, Pharmacology +9