Dermatology Practical & Conceptual · 2017 · 172 citations · 47 references
AgricultureNutritionNutritional SciencesClinical NutritionDietary AssessmentHuman NutritionDietary Supplement InformationHair DisordersMicronutrient RequirementsMicronutrient SupplementationNutrient Deficiency DisordersNutritional DeficienciesClinical Laboratory EvaluationComprehensive Medical HistoryDietary History AssessmentHair Loss EvaluationNutrient Deficiency DetectionNutrient Deficiency EffectsNutrient SupplementationRisk Factors For Deficiency
Patients presenting with hair loss should be screened by medical history, dietary history and physical exam for risk factors for nutrient deficiency. If warranted, laboratory studies may be performed. In patients with no risk factors, further laboratory evaluation searching for nutritional deficiencies is not warranted. For patients with nutritional deficiencies, it is clear that those deficiencies should be corrected. Further research is required to determine whether any benefit exists for nutrient supplementation in the absence of documented deficiency. At this time, patients must be informed that such research is lacking and that in fact some supplements carry the risk of worsening hair loss or the risk of toxicity.
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Paula R. Trumbo, Allison A. Yates, Sandra A. Schlicker et al. · Journal of the American Dietetic Association · 2001 · 4.9K citations
Sonic hedgehog signaling is essential for hair development
Benoit St‐Jacques, Hélène R. Dassule, Irina Karavanova et al. · Current Biology · 1998 · 777 citations
The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency
Xin Du, Ellen She, Terri Gelbart et al. · Science · 2008 · 575 citations · Full text