Intermittent convection-enhanced delivery of GDNF into rhesus monkey putamen: absence of local or cerebellar toxicity

Convection-enhanced delivery of macromolecules in the brain.

R. Hunt Bobo, Douglas W. Laske, Aytaç Akbaşak et al. · Proceedings of the National Academy of Sciences · 1994 · 1.4K citations · Full text

Interstitial Infusion, Pharmaceutical Science, Neurophysiology +15

Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo

A. Tomac, Elisabet Lindqvist, L. Lin et al. · Nature · 1995 · 1.1K citations · Full text

Neurophysiology, Medicine, Neurotransmitter +11

Functional recovery in parkinsonian monkeys treated with GDNF

Don M. Gash, Zhiming Zhang, Aliza Ovadia et al. · Nature · 1996 · 963 citations

Functional Recovery, Neuropharmacology, Neurology +4

Glial cell line‐derived neurotrophic factor supports survival of injured midbrain dopaminergic neurons

Kathryn E. Bowenkamp, Alexander F. Hoffman, Greg A. Gerhardt et al. · The Journal of Comparative Neurology · 1995 · 292 citations

Glial Biology, Glial Cell, Cellular Neurobiology +19

Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys

Richard Grondin, Zhiming Zhang, Ai Yi et al. · Brain · 2002 · 282 citations · Full text

Social Sciences, Neuroregeneration, Neurology +17