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Publication | Open Access

FGFR4 Links Glucose Metabolism and Chemotherapy Resistance in Breast Cancer

DOIFull Paper Access

53

Citations

0

References

2018

Year

Min Xu, Shuzheng Chen, Weibin Yang, Xue Cheng, Yani Ye, Jianting Mao, Xulu Wu, Li Huang, Jiansong Ji
Cellular Physiology and Biochemistry

Abstract

Our findings suggest that high levels of FGFR4 can increase glucose metabolism and lead to chemoresistance in breast cancer and reveal the mechanistic basis for targeting FGFR4 as a therapeutic opportunity for chemoresistant tumors.