TGF-β Concentration in Breast Milk is Associated With the Development of Eczema in Infants

Yoshinori Morita, Eduardo Campos‐Alberto, Fumiya Yamaide, Taiji Nakano, Hidenori Ohnisi, Minako Kawamoto, Norio Kawamoto, Eiko Matsui, Naomi Kondo, Yoichi Kohno,

Frontiers in Pediatrics · 2018 · 34 citations · 25 references

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Abstract

Background: Transforming growth factor (TGF)- in breast milk is crucial for mucosal immune system in the neonatal period. We hypothesized that the level of exposure to TGF- from breast milk in the first month of life is related to the development of eczema later in life. Thus, the present study investigated whether changes in TGF- levels between colostrum and mature milk are associated with such occurrence in a birth cohort study.

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