The sVEGFR1-i13 splice variant regulates a β1 integrin/VEGFR autocrine loop involved in the progression and the response to anti-angiogenic therapies of squamous cell lung carcinoma - Concepedia

Concepedia

Publication | Open Access

The sVEGFR1-i13 splice variant regulates a β1 integrin/VEGFR autocrine loop involved in the progression and the response to anti-angiogenic therapies of squamous cell lung carcinoma

DOI Full Paper Access

19

Citations

30

References

2018

Year

Chérine Abou Fayçal, Élisabeth Brambilla, Jackeline Agorreta, Nina Lepeltier, Thibault Jacquet, Nicolas Lemaître, Anouk Emadali, Anthony Lucas, Pedro Miguel Lacal, Luis M. Montuenga,

British Journal of Cancer

Abstract

Overall, these results reveal an unexpected pro-tumoural function of sVEGFR1-i13 in SQLC tumour cells, which contributes to their progression and escape from anti-angiogenic therapies. These data might help to understand why some SQLC patients do not respond to anti-angiogenic therapies.

References

	Year	Citations

Page 1