Eurosurveillance · 2018 · 103 citations · 14 references
Life SciencesInfectious DiseasesMicrobiologyGenomicsMedical MicrobiologyMicrobial GeneticsAntibiotic ResistanceAntibiotic Resistance MechanismsAntimicrobial Resistance GenomicsBacterial InfectionsMultidrug ResistanceSexually Transmitted InfectionsAntimicrobial Resistance In GonorrheaBacterial Multidrug ResistanceCeftriaxone TherapyGenotypic ClassificationGenotypic IdentificationMultidrug Resistance DeterminantsMultidrug-resistant PathogensNeisseria Gonorrhoeae Resistance
We report a multidrug-resistant Neisseria gonorrhoeae urogenital and pharyngeal infection with ceftriaxone resistance and intermediate resistance to azithromycin in a heterosexual woman in her 20s in France. Treatment with ceftriaxone plus doxycycline failed for the pharyngeal localisation. Whole-genome sequencing of isolate F90 identified MLST 1903 , NG-MAST ST 3435 , NG-STAR 233 , and relevant resistance determinants. F90 showed phenotypic and genotypic similarities to an internationally spreading multidrug-resistant and ceftriaxone-resistant clone detected in Japan and subsequently in Australia, Canada and Denmark.
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QUAST: quality assessment tool for genome assemblies
Alexey Gurevich, Vladislav Saveliev, Nikolay Vyahhi et al. · Bioinformatics · 2013 · 11.5K citations · Full text
Magnus Unemo, Daniel Golparian, Robert A. Nicholas et al. · Antimicrobial Agents and Chemotherapy · 2011 · 642 citations