Mathematical Biosciences & Engineering · 2018 · 17 citations · 8 references
Natural SciencesMathematicsNeuroscienceDynamical SystemsNeural EngineeringNeurophysiologyDissipative SystemsKinetic ModelingNonlinear DynamicsStability TheoryTime-dependent KineticsBrain Energy Metabolism ModelingFast-slow Dynamical SystemsLactate KineticsLactate ProductionLinear StabilityLinear Stability AnalysisLinear Stability TheorySteady-state Solutions
The aim of this article is to study the well-posedness and properties of a fast-slow system which is related with brain lactate kinetics. In particular, we prove the existence and uniqueness of nonnegative solutions and obtain linear stability results. We also give numerical simulations with different values of the small parameter ε and compare them with experimental data.
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The aerobic brain: lactate decrease at the onset of neural activity
Silvia Mangia, Girolamo Garreffa, Marta Bianciardi et al. · Neuroscience · 2003 · 104 citations