Nitrated T helper cell epitopes enhance the immunogenicity of HER2 vaccine and induce anti-tumor immunity

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene

Dennis J. Slamon, Gary M. Clark, Steven Wong et al. · Science · 1987 · 11.7K citations

Medicine, Genetics, Oncology +14

Development of high potency universal DR-restricted helper epitopes by modification of high affinity DR-blocking peptides

Jeff Alexander, John Sidney, Scott Southwood et al. · Immunity · 1994 · 530 citations

Life Sciences, Immunology, Adaptive Immunity +11

High Risk of Recurrence for Patients With Breast Cancer Who Have Human Epidermal Growth Factor Receptor 2–Positive, Node-Negative Tumors 1 cm or Smaller

Ana M. González-Angulo, Jennifer K. Litton, Kristine Broglio et al. · Journal of Clinical Oncology · 2009 · 467 citations · Full text

Medicine, Oncology, Pathology +17

Immunization with a HER-2/neu helper peptide vaccine generates HER-2/neu CD8 T-cell immunity in cancer patients

Keith L. Knutson, Kathy Schiffman, Mary L. Disis · Journal of Clinical Investigation · 2001 · 450 citations · Full text

Life Sciences, Immunology, Oncology +17

Final report of the phase I/II clinical trial of the E75 (nelipepimut-S) vaccine with booster inoculations to prevent disease recurrence in high-risk breast cancer patients

EA Mittendorf, Guy T. Clifton, Jarrod P. Holmes et al. · Annals of Oncology · 2014 · 245 citations · Full text

Veterinary Medicine, Immunology, Oncology +17