Concepedia

The Roles of Matrix Stiffness and ß-Catenin Signaling in Endothelial-to-Mesenchymal Transition of Aortic Valve Endothelial Cells

Aileen Zhong, Zahra Mirzaei, Craig A. Simmons

Cardiovascular Engineering and Technology · 2018 · 83 citations · 25 references

DOI

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References

25

Matrix stiffness drives epithelial–mesenchymal transition and tumour metastasis through a TWIST1–G3BP2 mechanotransduction pathway

Spencer C. Wei, Laurent Fattet, Jeff H. Tsai et al. · Nature Cell Biology · 2015 · 973 citations · Full text

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Activated Interstitial Myofibroblasts Express Catabolic Enzymes and Mediate Matrix Remodeling in Myxomatous Heart Valves

Elena Rabkin, Masanori Aikawa, James R. Stone et al. · Circulation · 2001 · 617 citations · Full text

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Valvular Myofibroblast Activation by Transforming Growth Factor-β

Gennyne Walker, Kristyn S. Masters, Darshita N. Shah et al. · Circulation Research · 2004 · 396 citations

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The Wnt/β-catenin pathway regulates cardiac valve formation

Adam Hurlstone, Anna-Pavlina G. Haramis, Erno Wienholds et al. · Nature · 2003 · 392 citations

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β-Catenin is required for endothelial-mesenchymal transformation during heart cushion development in the mouse

Stefan Liebner, Anna Cattelino, R Gallini et al. · The Journal of Cell Biology · 2004 · 366 citations · Full text

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