Concepedia

Publication | Open Access

Effect of CXCR4 on Apoptosis in Osteosarcoma Cells via the PI3K/Akt/NF-κβ Signaling Pathway

DOIFull Paper Access

40

Citations

0

References

2018

Year

Chunming Jiang, Shenglin Ma, Runlei Hu, Xuepeng Wang, Maoqiang Li, Fei Tian, Wu Jiang, Liulong Zhu, Zhenyu Bian
Cellular Physiology and Biochemistry

Abstract

Taken together, the results demonstrated that down-regulation of CXCR4 could induce apoptosis of human osteosarcoma cells through inhibiting PI3K/Akt/NF-κβ signaling pathway, indicating that CXCR4 could be vital for the clinical therapy of osteosarcoma.