Concepedia

Clinical phase 1b study results for safety, pharmacokinetics and efficacy of ND-L02-s0201, a novel targeted lipid nanoparticle delivering HSP47 SIRNA for the treatment of Japanese patients with advanced liver fibrosis

Naoya Sakamoto, K Ogawa, Goki Suda, K. Morikawa, Takuya Sho, Masato Nakai, Hisashi Suzuki, N. Yamagata, Y. Tanaka, Wenbin Ying,

Journal of Hepatology · 2018 · 17 citations · 0 references

Concepts

PharmacyPharmaceuticsPharmacologyDrug DeliveryNanoparticle Drug DeliveryTargeted Drug DeliveryHepatic FibrosisLipid-based NanoparticlesLiver DiseaseNanocarriers For TherapeuticsNanomedicinePharmacokinetics In Liver DiseaseLipid Nanoparticle Delivery SystemsLipid Nanoparticle SynthesisLipid-based Nanoparticle FormulationLiver Fibrosis ProgressionLiver-specific Drug Targeting