Optogenetic reversible knocksideways, laser ablation, and photoactivation on the mitotic spindle in human cells

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

Andrew Fire, Siqun Xu, Mary K. Montgomery et al. · Nature · 1998 · 15.3K citations · Full text

Life Sciences, Genetics, Molecular Biology +8

Millisecond-timescale, genetically targeted optical control of neural activity

Edward S. Boyden, Feng Zhang, Ernst Bamberg et al. · Nature Neuroscience · 2005 · 4.9K citations

Life Sciences, Neurobiology, Neuroscience +12

Channelrhodopsin-2, a directly light-gated cation-selective membrane channel

Georg Nagel, Tanjef Szellas, Wolfram Huhn et al. · Proceedings of the National Academy of Sciences · 2003 · 2.7K citations · Full text

Life Sciences, Biology, Biophysics +17

Optogenetics

Karl Deisseroth · Nature Methods · 2010 · 1.8K citations · Full text

Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen

Thomas U. Mayer, Tarun M. Kapoor, Stephen J. Haggarty et al. · Science · 1999 · 1.7K citations

Life Sciences, Cell Biology, Molecular Biology +17