Proceedings of the National Academy of Sciences · 2018 · 150 citations · 42 references
Life SciencesPlant BiologyPlant SciencesGene ExpressionGene Regulatory NetworksTranscriptional RegulationPlant Defense ResponsesPlant Immune ResponsesPlant Immune SignalingPlant Transcriptional RegulationRoot DevelopmentRoot PhysiologyBiotic StressBiotic Stress TranscriptomicsMyb Transcription FactorsRoot Cell ElongationRoot Growth RegulationRoot TranscriptomicsTranscriptional Regulatory NetworksVery-long-chain Fatty Acids
Significance Plant roots tune their growth to the environment. An important class of molecules involved in environmental responses as well as in root growth regulation is composed of reactive oxygen species (ROS). By making use of a comprehensive transcriptome atlas capturing ROS responses in different developmental zones of the root, we uncovered a regulatory network that is involved in root-growth regulation and responses to biotic stress. This network is composed of the ROS-responsive transcription factor MYB30, which regulates multiple genes involved in the transport of very-long-chain fatty acids (VLCFAs). Overall, our findings show that Arabidopsis uses the same MYB30 -dependent regulatory network for root-growth and immunity responses, processes that were considered largely independent of each other.
42
In silico prediction of protein-protein interactions in human macrophages
Oussema Souiai, Fatma Z. Guerfali, Slimane Ben Miled et al. · BMC Research Notes · 2014 · 11K citations · Full text