Ebselen protects mitochondrial function and oxidative stress while inhibiting the mitochondrial apoptosis pathway after acute spinal cord injury

Mitochondrial damage induced by conditions of oxidative stress

Alicia J. Kowaltowski, Anı́bal E. Vercesi · Free Radical Biology and Medicine · 1999 · 869 citations

Life Sciences, Biochemistry, Cell Biology +14

Impaired mitochondrial function, oxidative stress and altered antioxidant enzyme activities following traumatic spinal cord injury

Robert D. Azbill, Xiaojun Mu, Annadora J. Bruce‐Keller et al. · Brain Research · 1997 · 311 citations

Medicine, Neurobiology, Neuroscience +16

Safety and efficacy of ebselen for the prevention of noise-induced hearing loss: a randomised, double-blind, placebo-controlled, phase 2 trial

Jonathan Kil, Edward Lobariñas, Christopher Spankovich et al. · The Lancet · 2017 · 258 citations

Health Professions, Audiology, Otolaryngology +12

The early research and development of ebselen

Michael J. Parnham, Helmut Sies · Biochemical Pharmacology · 2013 · 229 citations

Engineering, Materials Engineering, Electronic Materials +1

Synthetic activation of caspases: Artificial death switches

Rebecca A. MacCorkle, Kevin W. Freeman, David M. Spencer · Proceedings of the National Academy of Sciences · 1998 · 188 citations

Life Sciences, Biotechnology, Cell Biology +16