Concepedia

The flavonoid compound apigenin prevents colonic inflammation and motor dysfunctions associated with high fat diet-induced obesity

Daniela Gentile, Matteo Fornai, Rocchina Colucci, Carolina Pellegrini, Erika Tirotta, Laura Benvenuti, Cristina Segnani, Chiara Ippolito, Emiliano Duranti, Agostino Virdis,

PLoS ONE · 2018 · 67 citations · 41 references

DOIFull text

Open access

Abstract

Apigenin prevents systemic metabolic alterations, counteracts enteric inflammation and normalizes colonic dysmotility associated with obesity.

References

41

High Fat Diet-Induced Gut Microbiota Exacerbates Inflammation and Obesity in Mice via the TLR4 Signaling Pathway

Kyung‐Ah Kim, Wan Gu, In‐Ah Lee et al. · PLoS ONE · 2012 · 1.1K citations · Full text

A guide to histomorphological evaluation of intestinal inflammation in mouse models.

Ulrike Erben, Christoph Loddenkemper, Katja Doerfel et al. · PubMed · 2014 · 688 citations · Full text

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Apigenin and cancer chemoprevention: Progress, potential and promise (Review)

Deendayal Patel, Sanjeev Shukla, Sanjay Gupta · International Journal of Oncology · 2007 · 523 citations · Full text

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A Mouse Model of Diet-Induced Obesity and Insulin Resistance

Chao‐Yung Wang, James K. Liao · Methods in molecular biology · 2011 · 520 citations

Flavonoid Apigenin Is an Inhibitor of the NAD+ase CD38

Carlos Escande, Verónica Nin, Nathan L. Price et al. · Diabetes · 2012 · 318 citations · Full text

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