Protective Role of the MER Tyrosine Kinase via Efferocytosis in Rheumatoid Arthritis Models - Concepedia

Concepedia

Publication | Open Access

Protective Role of the MER Tyrosine Kinase via Efferocytosis in Rheumatoid Arthritis Models

DOI Full Paper Access

67

Citations

46

References

2018

Year

Claire E. J. Waterborg, Silke Beermann, Mathijs G A Broeren, Miranda B. Bennink, Marije I. Koenders, Peter L. E. M. van Lent, Wim B. van den Berg, P.M. van der Kraan, Fons A. J. van de Loo

Frontiers in Immunology

Abstract

MER plays a protective role during joint inflammation and activating MER by its ligand PROS1 ameliorates disease. Treatment of mice with MER receptor agonistic antibodies is deleterious due to its counterproductive effect of blocking efferocytosis in the arthritic joint.

References

	Year	Citations

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