Lentivirus-mediated expression of human secreted amyloid precursor protein-alpha prevents development of memory and plasticity deficits in a mouse model of Alzheimer's disease

Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

Dave Morgan, David M. Diamond, Paul E. Gottschall et al. · Nature · 2000 · 1.5K citations

Vaccination, Neurodegenerative Diseases, Alzheimer's Disease +14

Object recognition in rats and mice: a one-trial non-matching-to-sample learning task to study 'recognition memory'

Rick A. Bevins, Joyce Besheer · Nature Protocols · 2006 · 1.2K citations

Behavioral Sciences, Cognitive Science, Neuropsychology +10

Severity of spatial learning impairment in aging: Development of a learning index for performance in the Morris water maze.

Michela Gallagher, Rebecca D. Burwell, Margaret Burchinal · Behavioral Neuroscience · 2015 · 871 citations · Full text

Neuropsychology, Aging, Brain Function +16

Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model

Jean‐Cosme Dodart, Kelly R. Bales, Kimberley S. Gannon et al. · Nature Neuroscience · 2002 · 857 citations

Immunology, Immunodominance, Social Sciences +19

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein

Mark P. Mattson, Bin Cheng, Alan R. Culwell et al. · Neuron · 1993 · 795 citations

Secreted Forms, Neurodegenerative Diseases, Molecular Neuroscience +12