Concepedia

Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model

Jean‐Cosme Dodart, Kelly R. Bales, Kimberley S. Gannon, Stephen J. Greene, Ronald B. DeMattos, Chantal Mathis, Cynthia DeLong, Su Wu, Xin Wu, David M. Holtzman,

Nature Neuroscience · 2002 · 859 citations · 21 references

DOI

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References

21

A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data

A. Ennaceur, Jean Delacour · Behavioural Brain Research · 1988 · 3.2K citations

, , +16

Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse

Dale Schenk, Robin Barbour, Whitney Dunn et al. · Nature · 1999 · 3.2K citations

, , +14

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

Dora Games, David S. Adams, Ree Alessandrini et al. · Nature · 1995 · 2.5K citations

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Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

Frédérique Bard, Catherine Cannon, Robin Barbour et al. · Nature Medicine · 2000 · 2K citations

, , +17

Soluble pool of A? amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

Catriona McLean, Robert A. Cherny, Fiona Fraser et al. · Annals of Neurology · 1999 · 1.8K citations

, , +17