Indeterminate pediatric acute liver failure is uniquely characterized by a CD103+CD8+ T‐cell infiltrate

Abstract

Indeterminate PALF is characterized by a dense CD8⁺ T-cell hepatic infiltrate consistent with expansion of a tissue resident memory T-cell phenotype; CD8⁺ T-cells are a biomarker of immune dysregulation in iPALF and may be used to better identify and define this group. (Hepatology 2018).