Long-term Air Pollution Exposure, Genome-wide DNA Methylation and Lung Function in the LifeLines Cohort Study

Abstract

Long-term NO₂ exposure was genome-wide significantly associated with DNA methylation in the identification cohort but not in the replication cohort. Future studies are needed to further elucidate the potential mechanisms underlying _NO₂-exposure-related respiratory disease. https://doi.org/10.1289/EHP2045.