Expression of miRNAs in Serum Exosomes versus Hippocampus in Methamphetamine‐Induced Rats and Intervention of Rhynchophylline

Abstract

Rhynchophylline blocked the alteration of behavior and the expression of some DE miRNAs induced by methamphetamine. The biological functions of these DE miRNAs target genes are correlated between serum exosomes and hippocampus. As to these biological processes and pathways which are involved in the development of addiction at multiple stages, we speculate that these DE miRNAs in serum exosomes and hippocampus are closely related to methamphetamine addiction.