High expression of COL10A1 is associated with poor prognosis in colorectal cancer

Haipeng Huang, Tingting Li, Gengtai Ye, Liying Zhao, Zhenzhan Zhang, Debin Mo, Yiming Wang, Ce Zhang, Haijun Deng, Guoxin Li,

OncoTargets and Therapy · 2018 · 87 citations · 26 references

DOIFull text

Open access

Abstract

Our findings had provided evidences to support the fact that COL10A1 was abnormally up-expressed in CRC and involved in the progression of CRC and the process of EMT. Furthermore, we demonstrated that the high-level expression of COL10A1 was an independent risk factor of prognosis and overall survival in CRC patients. These suggested that COL10A1 might be a new potential target for cancer therapy in the future.

References

26