Concepedia

Publication | Open Access

Reactive species balance via GTP cyclohydrolase I regulates glioblastoma growth and tumor initiating cell maintenance

DOIFull Paper Access

77

Citations

36

References

2018

Year

Anh Tran, Kiera Walker, David G. Harrison, Wei Chen, James A. Mobley, Lauren Hocevar, James R. Hackney, Randee Sedaka, Jennifer S. Pollock, Matthew S. Goldberg,
Neuro-Oncology

Abstract

GCH1 expression in established GBMs is pro-tumorigenic, causing increased growth due, in part, to promotion of BTIC maintenance and suppression of reactive oxygen species.

References

YearCitations

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