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Neuroprotective Effects of Creatine in the CMVMJD135 Mouse Model of Spinocerebellar Ataxia Type 3

Sara Duarte‐Silva, Andreia Neves‐Carvalho, Carina Soares‐Cunha, Joana Silva, Andreia Teixeira‐Castro, Rita Vieira, Anabela Silva‐Fernandes, Patrı́cia Maciel

Movement Disorders · 2018 · 34 citations · 33 references

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Abstract

Creatine slows disease progression and improves motor dysfunction as well as ameliorates neuropathology of the CMVMJD135 animals, supporting this as a useful strategy to slow the progression of spinocerebellar ataxia type 3. © 2018 International Parkinson and Movement Disorder Society.

References

33

Dose translation from animal to human studies revisited

Shannon Reagan‐Shaw, Minakshi Nihal, Nihal Ahmad · The FASEB Journal · 2007 · 6.1K citations

, , +19

Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis

Péter Klivènyi, Robert J. Ferrante, Russell T. Matthews et al. · Nature Medicine · 1999 · 684 citations

, , +10

Neuroprotective Effects of Creatine in a Transgenic Mouse Model of Huntington's Disease

Robert J. Ferrante, Ole A. Andreassen, Bruce G. Jenkins et al. · Journal of Neuroscience · 2000 · 517 citations · Full text

Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates.

Emmanuel Brouillet, Philippe Hantraye, Robert J. Ferrante et al. · Proceedings of the National Academy of Sciences · 1995 · 473 citations · Full text

, , +27

Creatine and Cyclocreatine Attenuate MPTP Neurotoxicity

Russell T. Matthews, Robert J. Ferrante, Péter Klivènyi et al. · Experimental Neurology · 1999 · 374 citations

, , +6