Silver nanoparticles <i>Clinacanthus Nutans</i> leaves extract induced apoptosis towards oral squamous cell carcinoma cell lines

Abstract

AgNps-CN have shown potential in inhibiting HSC-4 cell lines. IC₅₀ was low compared to few studies involving biosynthesized of silver nanoparticles. Apoptosis effects were shown towards HSC-4 cell lines by the increased in Bax/Bcl-2 protein ratio. Further study such as PCR or in vivo studies are required.