bioRxiv (Cold Spring Harbor Laboratory) · 2018 · 12 citations · 26 references
Life SciencesBioinformaticsCell BiologyGenomicsSingle-cell BioinformaticsTranscriptomicsSingle-cell AnalysisSingle-cell GenomicsSingle-cell Rna Sequencing AnalysisSingle-cell TranscriptomicsFlexibilitySingle-cell Rna Sequencing
Recent technological advances enable genomics of individual cells, the building blocks of all living organisms. Single cell data characteristics differ from those of bulk data, which led to a plethora of new analytical strategies. However, solutions are only useful for experts and currently, there are no widely accepted gold standards for single cell data analysis. To meet the requirements of analytical flexibility, ease of use and data security, we developed FASTGenomics ( https://fastgenomics.org ) as a powerful, efficient, versatile, robust, safe and intuitive analytical ecosystem for single-cell transcriptomics.
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The FAIR Guiding Principles for scientific data management and stewardship
Mark D. Wilkinson, Michel Dumontier, IJsbrand Jan Aalbersberg et al. · Scientific Data · 2016 · 17.8K citations · Full text
NCBI GEO: archive for functional genomics data sets—update
Tanya Barrett, Stephen E. Wilhite, Pierre Ledoux et al. · Nucleic Acids Research · 2012 · 10.8K citations · Full text
Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets
Evan Z. Macosko, Anindita Basu, Rahul Satija et al. · Cell · 2015 · 7.8K citations · Full text