Contractile responses to endothelin-1 are regulated by PKC phosphorylation of cardiac myosin binding protein-C in rat ventricular myocytes

PKC-α regulates cardiac contractility and propensity toward heart failure

Julian C. Braz, Kimberly N. Gregory, Anand Pathak et al. · Nature Medicine · 2004 · 593 citations

Medicine, Cardiology, Physiology +12

Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling

Xu Wu · Journal of Clinical Investigation · 2006 · 483 citations · Full text

Life Sciences, Cell Biology, Physiology +16

Increased Protein Kinase C Activity and Expression of Ca ²⁺ -Sensitive Isoforms in the Failing Human Heart

Nancy Bowling, Richard A. Walsh, Guojie Song et al. · Circulation · 1999 · 457 citations

Medicine, Cardiology, Physiology +10

A Protein Kinase C Translocation Inhibitor as an Isozyme-selective Antagonist of Cardiac Function

John A. Johnson, Mary O. Gray, Che-Hong Chen et al. · Journal of Biological Chemistry · 1996 · 381 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

Sustained <i>in vivo</i> cardiac protection by a rationally designed peptide that causes ɛ protein kinase C translocation

Gerald W. Dorn, Miriam C. Souroujon, Tamar Liron et al. · Proceedings of the National Academy of Sciences · 1999 · 364 citations · Full text

Medicine, Cardiology, Pharmacology +8