Concepedia

The desA and desB genes from Clostridium scindens ATCC 35704 encode steroid-17,20-desmolase

Saravanan Devendran, Sean M. Mythen, Jason M. Ridlon

Journal of Lipid Research · 2018 · 61 citations · 34 references

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Abstract

Substrate-specificity studies revealed that rDesAB recognized substrates regardless of 11β-hydroxylation, but had an absolute requirement for 17,21-dihydroxy 20-ketosteroids.

References

34

Revised Estimates for the Number of Human and Bacteria Cells in the Body

Ron Sender, Shai Fuchs, Ron Milo · PLoS Biology · 2016 · 5.1K citations · Full text

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The Moderately Efficient Enzyme: Evolutionary and Physicochemical Trends Shaping Enzyme Parameters

Arren Bar‐Even, Yonatan Savir, Wolfram Liebermeister et al. · Biochemistry · 2011 · 1.1K citations

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The human urinary microbiome; bacterial DNA in voided urine of asymptomatic adults

Debbie Lewis, Richard L. Brown, Jon Williams et al. · Frontiers in Cellular and Infection Microbiology · 2013 · 391 citations · Full text

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Androgens alter T-cell immunity by inhibiting T-helper 1 differentiation

Haydn Kissick, Martin G. Sanda, Laura Dunn et al. · Proceedings of the National Academy of Sciences · 2014 · 338 citations · Full text

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Clostridium scindens: a human gut microbe with a high potential to convert glucocorticoids into androgens

Jason M. Ridlon, Shigeo Ikegawa, João M. P. Alves et al. · Journal of Lipid Research · 2013 · 331 citations · Full text

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