Iodine promoted dual oxidative C(sp³)–H amination of 2-methyl-3-arylquinazolin-4(3<i>H</i>)-ones: a facile route to 1,4-diarylimidazo[1,5-<i>a</i>]quinazolin-5(4<i>H</i>)-ones

Abstract

)-H amination under metal free conditions in a greener way using molecular oxygen as a terminal oxidant. This tandem transformation provides an efficient approach to construct various functionalized imidazo[1,5-a]quinazolin-5(4H)-ones in a straightforward manner via a sequential amination-oxidation-annulation-aromatisation.