Associations between primary tumor <i>RAS</i>, <i>BRAF</i> and <i>PIK3CA</i> mutation status and metastatic site in patients with chemo-resistant metastatic colorectal cancer

Abstract

This study indicated that in patients with mCRC, RAS mutations are associated with increased risk of lung and ovary metastases. BRAF V600E is associated with increased risk of skin metastases, and PIK3CA mutation with decreased risk of peritoneal metastases.