Fiji: an open-source platform for biological-image analysis

Johannes Schindelin, Ignacio Arganda‐Carreras, Erwin Frise, +13

Nature Methods

BiologyBiological-image AnalysisImage AnalysisEngineeringMicroscope Image Processing +6

The Immunological Synapse: A Molecular Machine Controlling T Cell Activation

Arash Grakoui, Shannon K. Bromley, Cenk Sumen, +4

Science

Three-dimensional segregation of supramolecular activation clusters in T cells

Colin R. F. Monks, Benjamin A. Freiberg, Hannah Kupfer, +2

Nature

Signal TransductionCell DivisionCell InteractionSupramolecular Activation ClustersCytoskeleton +4

Detecting outliers when fitting data with nonlinear regression – a new method based on robust nonlinear regression and the false discovery rate

Harvey Motulsky, Ronald E. Brown

BMC Bioinformatics

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation

Michael R. Betts, Jason M. Brenchley, David A. Price, +4

Journal of Immunological Methods

Viable IdentificationAutoimmune DiseaseFlow Cytometric AssayImmunologyPathology +7

CD107a as a functional marker for the identification of natural killer cell activity

Galit Alter, Jessica Malenfant, Marcus Altfeld

Journal of Immunological Methods

Natural Killer CellsAutoimmune DiseaseFunctional MarkerImmunologyCell Death +8

T Cell Receptor-Proximal Signals Are Sustained in Peripheral Microclusters and Terminated in the Central Supramolecular Activation Cluster

Rajat Varma, Gabriele Campi, Tadashi Yokosuka, +2

Immunity

Signal TransductionTumor MicroenvironmentCell InteractionT-regulatory CellIntercellular Communication +6

Fast live-cell conventional fluorophore nanoscopy with ImageJ through super-resolution radial fluctuations

Nils Gustafsson, S J Culley, George W. Ashdown, +3

Nature Communications

Centrosome polarization delivers secretory granules to the immunological synapse

Jane C. Stinchcombe, Endre Majorovits, Giovanna Bossi, +2

Nature

Protein SecretionSignal TransductionMedicineSecretory GranulesCytoskeleton +6

Actin and agonist MHC–peptide complex–dependent T cell receptor microclusters as scaffolds for signaling

Gabriele Campi, Rajat Varma, Michael L. Dustin

The Journal of Experimental Medicine